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Indeed, many cells and organisms exposed to mild sub-lethal stress conditions trigger a protective response against stronger subsequent challenges

the only meaningful adverse event documented in research literature is mild scalp tingling in the first few applications, which resolves quickly

administered antibodies in vivo

conducted a pilot trial and demonstrated that one year of therapy with metformin improved the histological features of liver steatohepatitis (steatosis, inflammation and fibrosis), which was proven by biopsy [109]

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For instance, SGLT2 inhibitors may be added if first-line therapies such as diet and lifestyle changes plus metformin are insufficient