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Description
Partially modified retro-inverso-enkephalinamides: topochemical long-acting analogs in vitro and in vivo

We anticipated challenges in the literature search because this is an extremely data-rich area, and the work was to be done by a single researcher (SRs require a team)

Gastroenterology 116 , 593601 (1999)
Laboratory investigations using ionizing radiation-induced senescent cells demonstrate that FOXO4-DRI causes p53 nuclear exclusion and mitochondrial targeting, validating the proposed mechanism of selective senescent cell elimination through targeted protein-protein interaction disruption

Copper peptides support barrier function rather than disrupting it, making them potentially gentler than many other active ingredients

[PMC free article: PMC5372933] [PubMed: 28287490] 29
