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Lee, Harrison Chou, Zurabi Lominadze Journal of Clinical and Experimental Hepatology .2024

Isoleucine Isoleucine has proven its ability to increase muscle mass in humans and animals in some clinical trials.15 Generally, it makes up about half the amount of leucine in BCAA supplements

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doi: 10.1016/j.jid.2020.01.027 Egger A., Issa N., Kirsner R.S., Romanelli P., Issa N.T

(iii) the branched-chain -ketoacid dehydrogenase complex that is involved in the decarboxylation of ketoacids in the catabolic pathway of the branched-chain amino acids, namely leucine, isoleucine, and valine