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Participants were recreationally active (150 min/week of physical activity) but were not competitive athletes and were instructed not to alter their exercise regimen during the study

A systematic review of five trials, including 7,391 women and conducted before many countries instituted fortification of staple foods with folic acid, found that periconceptional folic acid supplementation, alone or with other micronutrients, was associated with a 69% lower risk of NTDs (relative risk [RR]: 0.31

Psychosocial support: Due to the social and psychological impact of the condition, counseling was offered to help the patient cope with the stigma of the odor and manage any associated anxiety

However, until now it was not known whether TMAO or its precursors could be involved in altered metabolic pathways that contribute to the risk of AF and HF

Dietary supplements should not be understood as a substitute for a varied diet