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Intravenous use should not be assumed unless a clinician specifically directs it

Because B12 is water-soluble, your body uses what it needs and passes most of the excess, and there is no established upper intake limit because harmful effects from high intake have not been well documented

That said, even with triple the vitamin B12 intake, pregnant mothers serum vitamin B12 dipped into the low-to-mid range of normal in this study

Stress, dietary factors, and absorption challenges can all contribute to depleted levels, leading to fatigue, brain fog, and low motivation

(PubMed) Bressa GM

Pooled effect sizes showed no difference between all routes of administration to increase Hb without substantial statistical evidence (Fig