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After adjustment for age, sex, apolipoprotein E 4 allele, plasma homocysteine concentration, and education level, subjects in the upper quartile of baseline plasma PC DHA levels, compared with subjects in the lower 3 quartiles, had a relative risk of 0.53 of developing all-cause dementia (95% confidence interval, 0.29-0.97

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At the same time, the complex regulation of GST activity is dependent on the transcriptional and post-translational regulation, which is orchestrated by several promoter elements and transcription factors, and by phosphorylation and S-glutathionylation, which may be dependent on light (Dixon and Edwards, 2010)

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