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Results We show that our model accurately reproduces published clinical and experimental data on the dose-dependent time course of acetaminophen in the plasma, the accumulation of acetaminophen and its metabolites in the urine, and the depletion of glutathione caused by conjugation with the toxic product

**Key Findings:** * The redesigned Grx1roGFP2 sensor exhibited improved fluorescence intensity, targetability, and maintained redox sensitivity

The etiology and ...

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