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DOI: 10.1196/annals.1320.010 Pennisi M, Malaguarnera G, Di Bartolo G, et al

Prior investigations have demonstrated that the gut microbiota provides immunological tissue and reduces the pathogenicity of microorganisms (Savage, 1970

[9,18] Although pharmacologic approaches are the most important treatment strategies for MDD, response rates to the first-line antidepressants are moderate and remission is observed in about 3045% of patients