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This may be linked to reduced intake of carbohydrates (including refined sugars, which directly affect the functionality of intestinal microbiota)

4.7 Iron Iron concentration is regulated by the hepcidin/ferroportin axis: liver hepcidin binds to tissue ferroportin, causing its internalization, blocking iron export, and therefore lowering serum concentration

It is recommended to use changes in diet and bulk forming medicines to control constipation before using this medicine

doi: 10.1159/000362724 68 CurryH