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4c), likely due to diminished condensin localization at highly transcribed genes and mitotically activated genes across the genome (Fig

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In contrast to these ineffective and nonspecific therapies, another therapeutic approach involving glutathione esters appears more specific and more promising

Pharmacokinetics and disposition of the kavalactone kawain: interaction with kava extract and kavalactones in vivo and in vitro

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Under the generation of ROS and increased oxidative stress with or without inhibition of the antioxidative glutathione system of the substantia nigra, PQ elicits mitochondrial dysfunction and injury, and eventually causes neurons to embark on cell death mechanisms (Yang and Tiffany-Castiglioni, 2005