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A.CalderaF.CeconeC.TrottaF.Garca-CarmonaF.et al (2020b)

Poor Nutrition: Without enough of the building blocks (the amino acids cysteine, glycine, and glutamate), the body cannot keep up with the demand

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The pH-sensitive characteristics of ionizable lipids confer endosomal escape activity to the LNPs, while the neutral surface of the LNPs in the physiological environment is beneficial for avoiding unspecific electrostatic interactions with biomaterials (Sun and Lu 2023)

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Sutter BM, Wu X, Laxman S, et al