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Description
Scientist, not medic
Although SIRT3-deficient mice showed bone loss and SIRT3 has been linked to the production of osteoclasts 63 , the function and importance of this protein in osteoblasts are incompletely understood

A 2025 systematic review in the American Journal of Sports Medicine confirmed preclinical support across tendon, ligament, muscle, and bone repair models while explicitly noting the absence of human clinical trial data (DOI: 10.1177/15563316251355551)
PPIs specifically have been shown to cause irregularities in magnesium status, small intestinal bacterial overgrowth and enteric infections including clostridium difficile, resulting in a 20% difference in bacterial taxa compared to non-users of these drugs which favours streptococcal abundance irrespective of H.pylori status

How to diagnose and classify tattoo complications in the clinic: a system of distinctive patterns
The better option depends on your symptoms, labs, health history, treatment goals, and provider evaluation
