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We observed significantly increased deacetylase activity of both SIRT1 and SIRT3 in the liver and spleen of mice treated with Ab68, but not with the non-inhibitory anti-CD38 antibody Ab69 (Fig

Some patients are trained to self-inject after the first few doses at the clinic

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We've seen firsthand how crucial this foundational understanding is for interpreting subsequent research observations

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Discovery of a novel NAMPT inhibitor that selectively targets NAPRT-deficient EMT-subtype cancer cells and alleviates chemotherapy-induced peripheral neuropathy