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Cancer, such as liver cancer , can disrupt B12 metabolism, resulting in high levels

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in vivo experiments in diabetic mice, compared to untreated islets, PLL-BR-coated islets led to the induction of an anti-inflammatory response featuring higher M2 macrophage markers levels and localized vascularization (189)

10.1093/infdis/jiac136 207

Cerebrospinal fluid levels of alphatocopherol in patients with multiple sclerosis

PMID 13360274