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Figures Abstract We have previously reported that acetylsalicylic acid (aspirin, ASA) induces cell cycle arrest, oxidative stress and mitochondrial dysfunction in HepG2 cells

The bulk RNA sequencing data generated in this study have been deposited in the Gene Expression Omnibus (GEO) for Mouse data (derived from C57BL/6 wild-type organoids): GSE310410 and Human organoid data: GSE310408

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Rectal glutathione delivery eliminates digestive tract and liver metabolism losses, providing 40-50% more bioavailability through rectal vasculature

& Aitken, R