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82 As a result, a much lower concentration of triple-conjugated system (C-dots-transferrin-epirubicin-temozolomide (C-DT)) was required to reduce tumor cell viability compared to non-transferrin systems (NT) and dual-conjugated systems, namely CDs-transferrin-temozolomide (C-TT) and CDs-transferrin-epirubicin (C-ET) (as shown in Figure 4B)

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The risks are substantial and include potential damage to the kidneys and liver, severe skin reactions, thyroid dysfunction, and issues with zinc levels

doi: 10.1016/j.coi.2009.03.001 28 LangrishCLChenYBlumenscheinWMMattsonJBashamBSedgwickJDet al

and studies investigating the role of glutamatergic agonists to combat NMDAR hypofunction and reduce symptoms [7]

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