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Loss of PRMT7 in the heart reduces symmetrical dimethylation of -catenin, enhances Wnt--catenin signaling, and promotes myocardial hypertrophy

10.1002/cphy.c130024 78 LingS.LiJ.ShanQ.DaiH.LuD.WenX.et al (2017)
Furthermore, excessive zinc disrupts zinc finger protein function by saturating binding sites, leading to protein misfolding and loss of DNA-binding specificity, which may further dysregulate immune gene expression

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2013 May;31(3):165-70