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The GMP Certification and authentic seal is also printed on the left bottom side of the bottle

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67 YangJ

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For example, biomineralized nanoparticles SBC@CaP derived from aging red blood cell vesicles and coated with pH-responsive calcium phosphate (CaP) shells, gradually dissolve the CaP layer in the acidic TME and expose the aging red blood cell membrane, enabling TAMs to selectively recognize and phagocytize them, achieving precise TAMs clearance, TME remodeling and immune activation thereby inhibiting tumor progression (55)

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Moreover, the contents of ATP and total glutathione (T-GSH) in the anisomycin-treated HuOCSCs were significantly decreased, while the contents of lipid peroxidation (LPO) and MDA were significantly higher than those in the control cells (Figure 1C)

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For the intestinal mechanical barrier hypothesis, gene silencing techniques could be used to specifically knock down key tight junction proteins (e.g., Occludin, ZO-1), or chemical agents could be applied to disrupt barrier integrity, thereby testing whether barrier restoration is a necessary prerequisite for TCM's efficacy

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