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Description
How PT-141 Works MC4R activation PT-141 binds melanocortin-4 receptors (with MC3R activity) in hypothalamic regions - the central hub for sexual motivation circuits

But the current study says that this is not the case

Saso, S
Nature , 351 , 491-494
Unraveling monogenic channelopathies and their implications for complex polygenic disease

Nature 479 , 547551 (2011)