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Progress in neuro-psychopharmacology & biological psychiatry

The area may itch or feel warm

An Overview of B12 Vitamin B12 is a powerhouse nutrient essential for maintaining nerve health and aiding in the production of DNA

Taking a proton pump inhibitor or other medications that reduce stomach acid for reflux or ulcers, as well as taking metformin for diabetes, can reduce absorption of B12 in food or supplements

Injections bypass the gut, and for these patients treatment is often a long-term maintenance strategy guided by their provider

Following the PRISMA guidelines and applying our inclusion criteria, we identified six studies eligible for inclusion in the metaanalysis (Figure 1)