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Impairment of mitochondrial anti-oxidant defence in SOD1-related motor neuron injury and amelioration by ebselen

In addition, inhibiting METTL17 significantly reduces mitochondrial RNA methylation, impairing the translation of mitochondrial protein-coding genes, affecting mitochondrial energy metabolism, and enhancing mitochondrial and intracellular ROS and lipid peroxidation levels

Ethics declarations Competing interests Yvonne Janssen-Heininger and Vikas Anathy hold patents: United States Patent No
K., Connelly J., Lindon J
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Nrf2-dependent glutamate-L-cysteine ligase catalytic subunit expression mediates insulin protection against hyperglycemia-induced brain endothelial cell apoptosis