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3 Challenges in diagnosis and treatment of neurodegenerative diseases 3.1 Diagnostic odyssey The diagnostic odyssey for rare neurodegenerative disorders is a lengthy and unpredictable process
Usually the diagnosis of PIP joint injury is evident just from the physical exam
doi: 10.1016/j.freeradbiomed.2023.02.015 [DOI] [PubMed] [Google Scholar] 82
Mater 10 (7), e2001689
The levels of IL-6 in the blood rise as chronic kidney disease progresses
in pyroptosis, the increase in ROS levels leads to the release of TXNIP from thioredoxin, promoting the activation of NLRP3 and subsequent inflammasome formation [191], while also enhancing the activation of caspase-1 and IL-1 [193, 194]
