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NON-OXIDATIVE PHASE of the PPP

5 Clinical implications and therapeutic targeting Tumor hypoxia and metabolic reprogramming have profound clinical implications, as they drive tumor aggressiveness, metastasis, immune evasion, and resistance to chemotherapy, radiotherapy, and targeted therapies

This difference corresponded to the decrease in levels of the Anpep-catalyzed products (cysteine and glycine) compared with serum and urine from control rats (Figures 3D,E, metabolite determination results are shown in Supplementary Tables S10)

doi: 10.1128/JVI.01001-07 201 YinHQuJPengQGanR

[DOI] [PMC free article] [PubMed] [Google Scholar] Leuchte HH, Baezner C, et al

Indian J Pharm Sci 86(4):514527 Philchenkov A (2018) Radiation-induced cell death: signaling and pharmacological modulation