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Indeed, excessive ROS disrupt the BBB integrity, impairing its selective permeability (Hu et al., 2020)
10.1007/s11101-024-09969-1 61
Lauroylcarnitine (C12-carnitine) can inhibit AMPK and secrete proinflammatory cytokines to promote the polarization of bone marrow-derived macrophages to the pro-inflammatory M1 phenotype [57]
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3.1.1 Tofacitinib Tofacitinib is an FDA-cleared JAK1/3 inhibitor for treating RA, PsA, and active ulcerative colitis
