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The magnitude of the DSST contribution is controlled by a combination of the above two factors

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Studies have shown that activated sirtuins transmit metabolic signals to a variety of proteins, including histones, via deacetylation, thereby mediating adaptive transcriptional reprogramming

10.1542/peds.2012-0310 Pediatrics 48 GorlachA.BertramK.HudecovaS.KrizanovaO

R.MilosoM.BragaM.NicoliniG.MorabitoA.PravettoniG.et al (1999)