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3) ITIM types (e.g., DCIR): CLRs with immunoreceptor tyrosine-based inhibitory motifs (ITIMs) negatively regulate signaling by other PRRs through the recruitment of SHP-1/2 phosphatases
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doi: 10.1124/jpet.102.035857
Cagrilintide activates amylin receptors (AMY1-3) in the brainstem (food intake reduction, leptin resensitization, gastric emptying delay)
The samples were incubated at 37 C for 4 h, after which they were centrifuged at 300 g min -1 for 10 min at 4 C
