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A., Ellis, L

Supply and demand: cellular nutrient uptake and exchange in cancer

Individuals with CBS mutations will be slow to make glutathione.33 Flipping this around, individuals who have slow methylation cycle enzymes will have lower homocysteine levels

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Mammalian TrxR1 was purified from calf liver as described previously ( 2.2 Construction, expression, and purification of site-directed mutants of TrxR1 The replacement of Sec498 by Cys and deletion of C-terminal Sec498 and Gly499 were performed according to a previously described method ( TCC CCG GGG AAG ACC CTA GTG GTT GG-3, and the reverse primer was 5- C CGG GGA GTA AGG CAA GGA GAA AAG ATC GT-3

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