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Destruction and reformation of an iron-sulfur cluster during catalysis by lipoyl synthase

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The oxidative stress and mitochondrial dysfunction during the pathogenesis of diabetic retinopathy

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Collectively, GLPs show strong therapeutic efficacy against retinal pathologies induced by ischemiareperfusion injury, acting via a multi-faceted pharmacological profile that includes antioxidant, anti-inflammatory, anti-apoptotic, anti-angiogenic, and gliosis-modulating activities