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Another extracellular mechanism for triggering cell death involves the interaction of receptors and ligands, such as the Fas/FasL system, which can also initiate apoptotic events under certain conditions (Yamada et al., 2017)

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Reversible covalent inhibitor GC376 was used as a positive control, which will not be removed by buffer exchange after covalent binding to 3CL

doi: 10.1038/emboj.2011.105
