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It means the product was never tested or manufactured to be injected into a person

For this reason, we start our investigation by probing in all-atom molecular dynamics simulations the stability of two A 40 and A 42 fibril models deposited in the Protein Data Bank (PDB), and we compare their stability with that of the corresponding DRI versions

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Despite the developments in ML, the interpretability of complex models and the need for validation in various patient populations pose challenges

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PMID: 224 JuricDKalinskyKTurnerNCJhaveriKLSchmidPLoiSet al