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High NNMT expression is closely associated with glucose dysregulation: excessive NNMT activation disrupts nicotinamide metabolism, lowers NAD+ levels, impairs insulin signaling, reduces cellular glucose uptake and utilization, and promotes hyperglycemia and insulin resistance

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[DOI] [PMC free article] [PubMed] [Google Scholar] 13.Zhang H, Majdeddin M, Degroote J, van Liefferinge E, van Noten N, van Kerschaver C, et al

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