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Type 2 diabetes In type 2 diabetes, metformin therapy is associated with B12 deficiency, resulting in a 10% higher risk of developing B12 depletion

Response timelines vary

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Preclinical studies using T4 (including the RGN-259 ophthalmic clinical trials) have not identified significant adverse events at therapeutic doses

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Play it safe if you: constantly feel tired despite getting enough sleep notice tingling or numbness, especially in your hands and feet are vegetarian or vegan regularly take acid blockers or metformin are over 60 years old Your doctor can determine whether you are affected with a simple blood testand advise you on the appropriate forms of therapy
