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These three compounds are frequently searched for as a set because they represent adjacent areas of research in metabolic and growth-hormone-axis peptides, even though their underlying mechanisms are distinct

A landmark study published in Science Translational Medicine in 2015 provided molecular evidence for this association

Decreased transcription of ChREBP-/ isoforms in abdominal subcutaneous adipose tissue of obese adolescents with prediabetes or early type 2 diabetes: associations with insulin resistance and hyperglycemia

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