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Description
Co-localization studies revealed that many of the DNA damage sites that are occupied by -H2AX did not co-localize with pNPM1 to efficiently repair all the damaged sites, which could in turn lead to tumor cell death
10.1016/j.bbapap.2015.01.014 Biochim
LynchAMGroveNCWagnerBDPalestineAGHolersVMFrazer-AbelAAet al
TGM2 is also remarkably specific for the glutamine residues that provide the substrate for the first step in the cross-linking reaction
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therefore, it is not certain that the same effects could be achieved in vivo
