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However, the data that show that the maximum intake of Se that had the greatest effect on COVID-19 cure rate in China (Reference Zhang, Bennett and Saad36) suggests that an intake above that required to optimise selenoproteins may be relevant to the mechanism by which Se affects SARS-CoV-2 and COVID-19

The epidemiology of CKD has been the subject of previous systematic reviews and meta-analyses [17,18,19], but in these studies, patients were only classified according to GFR status, making it difficult to quantify the true prevalence of a population at high or very high risk of progression to kidney failure or premature mortality