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Such studies should also consider the potential risk of infection or sepsis considering that treatment with canakinumab was found to be associated with a higher incidence of fatal infection in the CANTOS trial (419)

Natesan et al., 2016)

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10.1016/j.cplett.2009.07.088 10.1016/j.cplett.2009.07.088 [DOI] [Google Scholar] Jomova K, Makova M, Alomar SY, Alwasel SH, Nepovimova E, Kuca K, Rhodes CJ, Valko M (2022) Essential metals in health and disease

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