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Chronic Ethanol Consumption and Depression Disorders: A Review of the Evidence The relationship between chronic ethanol consumption and depression has been extensively documented in epidemiological, clinical, and neurobiological research, forming a cornerstone of our understanding of alcohols dual role as both a self-medicating agent and a neurotoxic driver of mood disorders (Gao 2022)

Tao L, Yang X, Ge C, Zhang P, He W, Xu X, Li X, Chen W, Yu Y, Zhang H, et al

This leads to decreased calcium levels in the blood (hypocalcemia) by suppressing the secretion of parathyroid hormone and increased renal excretion of calcium (hypercalciuria).

Cancer Epidemiol 92:102630

In the absence of GLS1 activity, Th1 cells display enhanced mTORC1 signaling, whereas Th17 cells show impaired activity