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Astrocytic uptake of -amyloid leads to it autophagic degradation, entrance of excess aspartate and ammonia into the urea cycle, increased putrescine and GABA production, with increased H 2 O 2 production and neuronal damage leading to cognitive deficits

Cystine: compartmentalization within lysosomes in cystinotic leukocytes

Morales A, Garca-Ruiz C, Miranda M, Mari M, Colell A, Ardite E, and Fernndez-Checa JC (1997)

33(Suppl.)245254

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