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Most of this corpus consists of cell-culture and rodent-model investigations

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Dysfunction of intestinal epithelial cell polarity and function can trigger potent inflammatory responses within the gut, and related to this, mice deficient in Ap1m2, a master regulator of intestinal epithelial cell polarization, demonstrate chronic colitis

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Any medication adjustments, including changes to the tirzepatide dose or titration schedule, should be made under healthcare provider guidance based on overall tolerability and treatment goals

1994;54:PL638