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The honest answer is that vitamin B12 deficiency recovery depends on what caused the low level and how long symptoms have been building

Cyanocobalamin can also be prescribed to treat pernicious anemia, a condition where the body is unable to absorb sufficient amounts of vitamin B12 from food

In this context, thanks to the high sensitivity (almost 100%) of quantitative ELISA, D-dimer measurement plays a key role in the diagnostic workup

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The main disadvantage of the microbiological method, however, is its low specificity as it measures a variety of cobalamin analogs that are not necessarily biologically active (Sobczynska-Malefora et al., 2021)

One study, which also evaluated cognitive function in patients with high MMA concentrations, found no significant effects on the MDD inventory score, but only 30 of the 140 subjects had depression at baseline, which may have diluted any benefits