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Lifestyle Factors In the REDEFINE trials CagriSema was studied alongside a reduced-calorie diet and increased physical activity the pharmacology is designed to support behavior change, not replace it [1]

Per CMS NCCI Policy Manual Chapter IV effective January 1, 2026, the same-joint arthroscopy bundling restriction for CPT codes 20600 through 20611 is an absolute restriction with no modifier override

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