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doi: 10.1093/ajcn/nqaa188

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Red Blood Cell Formation and Oxygen Transport B12 is required for the synthesis of DNA in rapidly dividing red blood cells

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Many people particularly those over 50, those with gastrointestinal conditions, or those taking certain medications like metformin or proton pump inhibitors have impaired intrinsic factor production and absorb far less B12 from supplements than labels suggest
