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The clinical trials of TwHF were summarized in Table 1

Finally, a study based on single-cell RNAseq has identified eight distinct T cell clusters, of which one uniquely present in SSc skin This CD4+ T cell subset is characterized by the expression of CXCL13 and IL-21 in addition to an T FH -like gene expression signature and that appears to be poised to promote B-cell responses within the inflamed skin of patients

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as a hydrophilic molecule, GSH is added to other lipophilic toxins or wastes prior to entering biliary excretion

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