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doi: 10.1016/j.cmet.2009.02.002

R.MukhiD.WattM.EdmundsL.XieB.CapoociJ.et al (2020)

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confirmed that supplementing a high-cholinergic diet with it can reduce plasma TMAO levels (from 22.1 M to 15.9 M), inhibit the formation of foam cells in mice, and prevent the progression of aortic root plaques ( in vivo rate of thrombus formation ( New choline TMA lyase inhibitors, including iodomethylcholine (IMC) and fluoromethylcholine (FMC), have been developed

Moreover, T2DM patients with elevated urinary HCR were found to be at higher risk of progressing to ESKD

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