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Description
Gastrointestinal disturbances such as constipation, gas, or diarrhea
This is a mechanism to protect sensitive protein thiols from irreversible oxidation and may also serve to prevent loss of GSH under oxidative conditions (Figure 2)

TB-500, in particular, is well known for its high solubility in water, making it easy to dissolve
E.et al (2009)
In this study, liver Kupffer cells were found to be a source of RELM-, and expression in both colon and Kupffer cells was increased by the deficient diet and was necessary for full manifestation of the disease

You might notice a bit of redness, itching, or slight irritation at the site
