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Manetti et al., 2010

Relapsed acute myeloid leukemia is less sensitive to venetoclax+ azacitidine due to leukemia stem cell resistance driven by fatty acid metabolism and can be overcome by pharmacologic inhibition of CPT1

10.1038/mp.2016.196 24 CatalaA.DiazM
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To explore this hypothesis, the expression pattern of the molecular machinery required to mediate the activity of Rspondins and Dkk2 was assessed in wild-type mice (Fig

If it was there would be signs of tolerance by the time but the neurogenic effect takes place over time
