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You might not even notice at first, and that is because your body needs time to build those stores back up

Retrieved from Usach, I., Martinez, R., Festini, T., & Peris, J

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As far as side effects are concerned, there's not much clarity

Under normal conditions, NNMT activity can consume substantial amounts of both nicotinamide and SAM, particularly in metabolically active tissues or during periods of metabolic stress

Therefore, the methylation of NA catalyzed by NNMT is inhibited, and the product, MNA, is reduced