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High fat diet induces gut dysbiosis and impairs the gut barrier, which enhances LPS or pathogen translocation into the circulation, causing endotoxemia that stimulates the release of systemic proinflammatory cytokines (Cani et al

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2017;96:e7653

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Next, we depleted HSF-1 in somatic tissues, using an auxin-inducible degron (AID) system 26 and confirmed that heat shock-induced expression of hsp-4p::gfp reporter requires HSF-1 activity (Fig

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Prognostic significance of metabolomic biomarkers in patients with diabetes mellitus and coronary artery disease, Karagiannidis E

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