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The ADCs approved or under development for NSCLC and their major clinical findings are summarized in Table 1
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Additionally, since ferroptosis intersects with various normal physiological signals such as ROS signaling, systemic long-term inhibition of ferroptosis may interfere with normal cellular functions or even weaken the bodys natural defense response against pathologies like tumors (Xu H
Antioxid (Basel) 12(11):1937
10.1016/j.ejphar.2010.12.024 87 MatochikJ
