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Without treatment, pellagra can be fatal, which is an important factor to be considered, since its low prevalence in developed countries causes missed diagnosis and delayed treatments (, , , )

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Validation of the Rabbit Telemetry Model for Cardiovascular Safety Pharmacology studies
Moore et al., 2019), Canadian women of reproductive age (Aljaadi et al., 2019) and older adults (Whitfield et al., 2019), Spanish adults (Mataix et al., 2003

Moreover, phosphatidylcholine (300 mg/kg, p.o., five times a week for 4 weeks) reduced the level of MDA and prevented the OXA-induced decreases of SOD, GPx, as well as GSH levels in SD rats (Kim et al., 2015)